8Y53

Cryo-EM structure of the MK-5046-bound BRS3-Gq complex

This is a non-PDB format compatible entry.

Summary for 8Y53

• Entry DOI: 10.2210/pdb8y53/pdb
• EMDB information: 38929
• Descriptor: Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, scFv16, ... (7 entities in total)
• Functional Keywords: gpcr, bombesin receptor subtype-3 receptor, mk-5046, membrane protein/immune system, membrane protein-immune system complex
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 170838.11

Authors

Li, C.,Xu, Y.,Yin, W.,Xu, H.E. (deposition date: 2024-01-31, release date: 2024-09-11)

• Primary citation: Li, C.,Xu, Y.,Su, W.,He, X.,Li, J.,Li, X.,Xu, H.E.,Yin, W.; Structural insights into ligand recognition, selectivity, and activation of bombesin receptor subtype-3.; Cell Rep, 43:114511-114511, 2024; PubMed: 39024101; DOI: 10.1016/j.celrep.2024.114511

Experimental method

ELECTRON MICROSCOPY (2.93 Å)