8Y2C

Cryo-EM structure of human dopamine transporter in apo state

Summary for 8Y2C

Entry DOI	10.2210/pdb8y2c/pdb
EMDB information	38850
Descriptor	Sodium-dependent dopamine transporter, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
Functional Keywords	human dopamine transporter in apo state, membrane protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	62032.92
Authors	Zhao, Y.,Li, Y. (deposition date: 2024-01-25, release date: 2024-08-14, Last modification date: 2024-08-28)
Primary citation	Li, Y.,Wang, X.,Meng, Y.,Hu, T.,Zhao, J.,Li, R.,Bai, Q.,Yuan, P.,Han, J.,Hao, K.,Wei, Y.,Qiu, Y.,Li, N.,Zhao, Y. Dopamine reuptake and inhibitory mechanisms in human dopamine transporter. Nature, 632:686-694, 2024 Cited by PubMed: 39112701 DOI: 10.1038/s41586-024-07796-0 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.16 Å)

Structure validation