8Y1V
Structure of GluN1b-GluN2D NMDA receptor in complex with competitive antagonist R-CPP and allosteric inhibitor YY-23
This is a non-PDB format compatible entry.
Summary for 8Y1V
| Entry DOI | 10.2210/pdb8y1v/pdb |
| EMDB information | 38847 |
| Descriptor | Isoform 6 of Glutamate receptor ionotropic, NMDA 1, Glutamate receptor ionotropic, NMDA 2D, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
| Functional Keywords | ion channel, calcium permeable, glutamate receptor, neuronal expression, membrane protein, membrane protein-inhibitor complex, membrane protein/inhibitor |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 395740.92 |
| Authors | |
| Primary citation | Zhang, J.L.,Zhu, S.J.,Fei, G. A novel antidepressant acting via allosteric inhibition of GluN2D-incorporated NMDA receptors at GABAergic interneurons To Be Published, |
| Experimental method | ELECTRON MICROSCOPY (4.2 Å) |
Structure validation
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