8XVI
Cryo-EM structure of ETAR bound with Endothelin1
Summary for 8XVI
Entry DOI | 10.2210/pdb8xvi/pdb |
EMDB information | 38705 |
Descriptor | Isoform Gnas-2 of Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total) |
Functional Keywords | gpcr, complex, eta, endothelin-1, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 173805.73 |
Authors | |
Primary citation | Hou, J.,Liu, S.,Zhang, X.,Tu, G.,Wu, L.,Zhang, Y.,Yang, H.,Li, X.,Liu, J.,Jiang, L.,Tan, Q.,Bai, F.,Liu, Z.,Miao, C.,Hua, T.,Luo, Z. Structural basis of antagonist selectivity in endothelin receptors. Cell Discov, 10:79-79, 2024 Cited by PubMed: 39075075DOI: 10.1038/s41421-024-00705-9 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.32 Å) |
Structure validation
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