8XV9
Fedratinib-bound human SLC19A3
Summary for 8XV9
Entry DOI | 10.2210/pdb8xv9/pdb |
EMDB information | 38693 |
Descriptor | Soluble cytochrome b562,Thiamine transporter 2, N-tert-butyl-3-{[5-methyl-2-({4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)pyrimidin-4-yl]amino}benzenesulfonamide (2 entities in total) |
Functional Keywords | slc19a3, fedratinib, transport protein |
Biological source | Escherichia coli More |
Total number of polymer chains | 1 |
Total formula weight | 68434.69 |
Authors | Dang, Y.,Wang, G.P.,Zhang, Z. (deposition date: 2024-01-14, release date: 2024-03-27, Last modification date: 2024-06-12) |
Primary citation | Dang, Y.,Zhang, T.,Pidathala, S.,Wang, G.,Wang, Y.,Chen, N.,Song, C.,Lee, C.H.,Zhang, Z. Substrate and drug recognition mechanisms of SLC19A3. Cell Res., 34:458-461, 2024 Cited by PubMed: 38503960DOI: 10.1038/s41422-024-00951-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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