8XPU

Overall structure of the LAT1-4F2hc bound with JPH203

8XPU の概要

• エントリーDOI: 10.2210/pdb8xpu/pdb
• EMDBエントリー: 38561
• 分子名称: Isoform 5 of Amino acid transporter heavy chain SLC3A2, Large neutral amino acids transporter small subunit 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: transporter, slc family, inhibitor, transport protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 129517.65

構造登録者

Hu, Z.,Yan, R. (登録日: 2024-01-04, 公開日: 2024-07-17, 最終更新日: 2024-07-31)

• 主引用文献: Hu, Z.,Yan, R.; Structural basis for the inhibition mechanism of LAT1-4F2hc complex by JPH203.; Cell Discov, 10:73-73, 2024; PubMed: 38956038; DOI: 10.1038/s41421-024-00697-6

実験手法

ELECTRON MICROSCOPY (3.3 Å)