8XOH

Cryo-EM structure of GPR30-Gq complex structure in the presence of E2

Summary for 8XOH

• Entry DOI: 10.2210/pdb8xoh/pdb
• EMDB information: 38529
• Descriptor: Guanine nucleotide-binding protein G(q) subunit alpha-q, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, scFv16, ... (5 entities in total)
• Functional Keywords: gpcr, estrogen, gpr30, gq, membrane protein, membrane protein-immune system complex, membrane protein/immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 5
• Total formula weight: 156822.49

Authors

Liu, H.,Xu, P.,Xu, H.E. (deposition date: 2024-01-01, release date: 2024-04-10, Last modification date: 2024-07-03)

• Primary citation: Liu, H.,Guo, S.,Dai, A.,Xu, P.,Li, X.,Huang, S.,He, X.,Wu, K.,Zhang, X.,Yang, D.,Xie, X.,Xu, H.E.; Structural and functional evidence that GPR30 is not a direct estrogen receptor.; Cell Res., 2024; PubMed: 38744981; DOI: 10.1038/s41422-024-00963-y

Experimental method

ELECTRON MICROSCOPY (3.2 Å)