8XM7

Cryo-EM structure of the RhoG/DOCK5/ELMO1/Rac1 complex: RhoG/DOCK5/ELMO1 focused map

Summary for 8XM7

Entry DOI	10.2210/pdb8xm7/pdb
EMDB information	38466
Descriptor	Engulfment and cell motility protein 1, Dedicator of cytokinesis protein 5, Rho-related GTP-binding protein RhoG, ... (5 entities in total)
Functional Keywords	elmo, dock, gef, gtpase, rho, rac, signaling protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	298739.69
Authors	Kukimoto-Niino, M.,Katsura, K.,Ishizuka-Katsura, Y.,Mishima-Tsumagari, C.,Yonemochi, M.,Inoue, M.,Nakagawa, R.,Kaushik, R.,Zhang, K.Y.J.,Shirouzu, M. (deposition date: 2023-12-27, release date: 2024-06-26, Last modification date: 2024-07-17)
Primary citation	Kukimoto-Niino, M.,Katsura, K.,Ishizuka-Katsura, Y.,Mishima-Tsumagari, C.,Yonemochi, M.,Inoue, M.,Nakagawa, R.,Kaushik, R.,Zhang, K.Y.J.,Shirouzu, M. RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state. J.Biol.Chem., 300:107459-107459, 2024 Cited by PubMed: 38857861 DOI: 10.1016/j.jbc.2024.107459 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.91 Å)

Structure validation