8XB2
Structure of radafaxine-bound state of the human Norepinephrine Transporter
Summary for 8XB2
Entry DOI | 10.2210/pdb8xb2/pdb |
EMDB information | 38208 |
Descriptor | GFP-MBP-solute carrier family 6 member 2,Maltose/maltodextrin-binding periplasmic protein,Sodium-dependent noradrenaline transporter,Maltose/maltodextrin-binding periplasmic protein,Sodium-dependent noradrenaline transporter, 2-acetamido-2-deoxy-beta-D-glucopyranose, (2~{S},3~{S})-2-(3-chlorophenyl)-3,5,5-trimethyl-morpholin-2-ol (3 entities in total) |
Functional Keywords | antidepressant, bupropion, transport protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 1 |
Total formula weight | 139173.97 |
Authors | |
Primary citation | Ji, W.M.,Wu, J.X. Substrate binding and inhibition mechanism of norepinephrine transporter To Be Published, |
Experimental method | ELECTRON MICROSCOPY (3.04 Å) |
Structure validation
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