8X5Y
CryoEM structure of the histamine H1 receptor-BRIL/Anti BRIL Fab complex with astemizole
Summary for 8X5Y
Entry DOI | 10.2210/pdb8x5y/pdb |
EMDB information | 38075 |
Descriptor | Histamine H1 receptor,Soluble cytochrome b562, 1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-benzimidazol-2-amine (2 entities in total) |
Functional Keywords | gpcr, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 1 |
Total formula weight | 51087.93 |
Authors | |
Primary citation | Wang, D.,Guo, Q.,Wu, Z.,Li, M.,He, B.,Du, Y.,Zhang, K.,Tao, Y. Molecular mechanism of antihistamines recognition and regulation of the histamine H 1 receptor. Nat Commun, 15:84-84, 2024 Cited by PubMed: 38167898DOI: 10.1038/s41467-023-44477-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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