8X2D

Crystal structure of H5 hemagglutinin from swan-infecting H5N8 influenza virus complexed with avian receptor analog LSTc

Summary for 8X2D

Entry DOI	10.2210/pdb8x2d/pdb
Related PRD ID	PRD_900046
Descriptor	Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	viral protein-immune system complex, viral protein/immune system
Biological source	Influenza A virus
Total number of polymer chains	3
Total formula weight	177473.97
Authors	Jin, X.Y.,Han, P.,Song, H.,Qi, J.X. (deposition date: 2023-11-09, release date: 2025-05-14)
Primary citation	Jin, X.,Han, P.,Zhang, C.,Miao, A.D.,Shi, Y.,Qi, J.,Bi, Y.,Liu, Y.,Song, H.,Gao, G.F. Enhanced binding of Sialyl Lewis X to hemagglutinin contributes to H5N8 mammalian pathogenicity and infectivity To Be Published,
Experimental method	X-RAY DIFFRACTION (2.48 Å)

Structure validation