8WUY

Crystal Structure of TR3 LBD in complex with para-positioned 3,4,5-trisubstituted benzene derivatives

8WUY の概要

• エントリーDOI: 10.2210/pdb8wuy/pdb
• 分子名称: Nuclear receptor subfamily 4immunitygroup A member 1, ~{N}-methyl-~{N}-octyl-3,4,5-tris(oxidanyl)benzamide (3 entities in total)
• 機能のキーワード: complex, transcription
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 55381.30

構造登録者

Hong, W.B.,Chen, X.Q.,Lin, T.W. (登録日: 2023-10-21, 公開日: 2024-01-24, 最終更新日: 2024-01-31)

• 主引用文献: Hong, W.,Xiao, T.,Lin, G.,Liu, C.,Li, H.,Li, Y.,Hu, H.,Wu, S.,Wang, S.,Liang, Z.,Lin, T.,Liu, J.,Chen, X.; Structure-based design and synthesis of anti-fibrotic compounds derived from para-positioned 3,4,5-trisubstituted benzene.; Bioorg.Chem., 144:107113-107113, 2024; PubMed: 38232685; DOI: 10.1016/j.bioorg.2024.107113

実験手法

X-RAY DIFFRACTION (2.6 Å)