8WSN

Crystal structure of SFTSV Gn and antibody SF1

Summary for 8WSN

• Entry DOI: 10.2210/pdb8wsn/pdb
• Descriptor: Gn, Ab1-H, Ab1-L, ... (6 entities in total)
• Functional Keywords: virus, antibody, viral protein/immune system, viral protein-immune system complex
• Biological source: SFTS virus JS4; More
• Total number of polymer chains: 6
• Total formula weight: 170753.40

Authors

Chang, Z.,Gao, F.,Wu, Y. (deposition date: 2023-10-17, release date: 2024-06-12)

• Primary citation: Chang, Z.,Gao, D.,Liao, L.,Sun, J.,Zhang, G.,Zhang, X.,Wang, F.,Li, C.,Oladejo, B.O.,Li, S.,Chai, Y.,Hu, Y.,Lu, X.,Xiao, H.,Qi, J.,Chen, Z.,Gao, F.,Wu, Y.; Bispecific antibodies targeting two glycoproteins on SFTSV exhibit synergistic neutralization and protection in a mouse model.; Proc.Natl.Acad.Sci.USA, 121:e2400163121-e2400163121, 2024; PubMed: 38830098; DOI: 10.1073/pnas.2400163121

Experimental method

X-RAY DIFFRACTION (2.8 Å)