8WQB
Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 2)
Summary for 8WQB
Entry DOI | 10.2210/pdb8wqb/pdb |
EMDB information | 37737 |
Descriptor | Cullin-2, Elongin-C, Elongin-B, ... (7 entities in total) |
Functional Keywords | e3 ubiquitin ligase, pro/c-degron, ligase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 11 |
Total formula weight | 388931.79 |
Authors | |
Primary citation | Chen, X.,Raiff, A.,Li, S.,Guo, Q.,Zhang, J.,Zhou, H.,Timms, R.T.,Yao, X.,Elledge, S.J.,Koren, I.,Zhang, K.,Xu, C. Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase. Nat Commun, 15:3558-3558, 2024 Cited by PubMed: 38670995DOI: 10.1038/s41467-024-47890-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.37 Å) |
Structure validation
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