8WM9
Fzd4/DEP complex
Summary for 8WM9
Entry DOI | 10.2210/pdb8wm9/pdb |
EMDB information | 37646 |
Descriptor | Frizzled-4, Segment polarity protein dishevelled homolog DVL-2, CHOLESTEROL HEMISUCCINATE (3 entities in total) |
Functional Keywords | gpcr complex, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 203999.06 |
Authors | |
Primary citation | Qian, Y.,Ma, Z.,Xu, Z.,Duan, Y.,Xiong, Y.,Xia, R.,Zhu, X.,Zhang, Z.,Tian, X.,Yin, H.,Liu, J.,Song, J.,Lu, Y.,Zhang, A.,Guo, C.,Jin, L.,Kim, W.J.,Ke, J.,Xu, F.,Huang, Z.,He, Y. Structural basis of Frizzled 4 in recognition of Dishevelled 2 unveils mechanism of WNT signaling activation. Nat Commun, 15:7644-7644, 2024 Cited by PubMed: 39223191DOI: 10.1038/s41467-024-52174-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.53 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)