8WII
Crystal structure of E. coli ThrS catalytic domain mutant G463A in complex with Obafluorin
Summary for 8WII
Entry DOI | 10.2210/pdb8wii/pdb |
Descriptor | Threonine--tRNA ligase, ~{N}-[(2~{R},3~{S})-2-[(4-nitrophenyl)methyl]-4-oxidanylidene-oxetan-3-yl]-2,3-bis(oxidanyl)benzamide, ZINC ION (3 entities in total) |
Functional Keywords | threonine--trna ligase, ligase |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 96730.51 |
Authors | |
Primary citation | Qiao, H.,Wang, Z.,Yang, H.,Xia, M.,Yang, G.,Bai, F.,Wang, J.,Fang, P. Specific glycine-dependent enzyme motion determines the potency of conformation selective inhibitors of threonyl-tRNA synthetase. Commun Biol, 7:867-867, 2024 Cited by PubMed: 39014102DOI: 10.1038/s42003-024-06559-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.98 Å) |
Structure validation
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