8WIG

Crystal structure of E. coli ThrS catalytic domain mutant G463S/Q484A

Summary for 8WIG

• Entry DOI: 10.2210/pdb8wig/pdb
• Descriptor: Threonine--tRNA ligase, ZINC ION (2 entities in total)
• Functional Keywords: threonine--trna ligase, ligase
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 95931.80

Authors

Qiao, H.,Wang, Z.,Wang, J.,Fang, P. (deposition date: 2023-09-24, release date: 2024-07-24)

• Primary citation: Qiao, H.,Wang, Z.,Yang, H.,Xia, M.,Yang, G.,Bai, F.,Wang, J.,Fang, P.; Specific glycine-dependent enzyme motion determines the potency of conformation selective inhibitors of threonyl-tRNA synthetase.; Commun Biol, 7:867-867, 2024; PubMed: 39014102; DOI: 10.1038/s42003-024-06559-x

Experimental method

X-RAY DIFFRACTION (3.22 Å)