8WGO

Cryo-EM structure of ClassIII Lanthipeptide modification enzyme PneKC in the presence of PneA and GTPrS.

Summary for 8WGO

Entry DOI	10.2210/pdb8wgo/pdb
EMDB information	37514
Descriptor	Protein kinase domain-containing protein, SapB/AmfS family lantipeptide, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	lanthibiotic, ripps, lankc, cryoem, antimicrobial peptides, antiviral peptides., antimicrobial protein
Biological source	Streptococcus pneumoniae More
Total number of polymer chains	3
Total formula weight	206796.29
Authors	Li, Y.,Luo, M.,Shao, K.,Li, J. (deposition date: 2023-09-22, release date: 2024-08-28)
Primary citation	Li, Y.,Shao, K.,Li, Z.,Zhu, K.,Gan, B.K.,Shi, J.,Xiao, Y.,Luo, M. Mechanistic insights into lanthipeptide modification by a distinct subclass of LanKC enzyme that forms dimers. Nat Commun, 15:7090-7090, 2024 Cited by PubMed: 39154050 DOI: 10.1038/s41467-024-51600-6 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.7 Å)

Structure validation