8WE3
Crystal structure of human FABP4 complexed with C7
Summary for 8WE3
Entry DOI | 10.2210/pdb8we3/pdb |
Descriptor | Fatty acid-binding protein, adipocyte, 2-[(3-chloranyl-2-phenyl-phenyl)amino]-5-fluoranyl-benzoic acid (3 entities in total) |
Functional Keywords | lipid binding protein-inhibitor complex, lipid binding protein/inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 17253.03 |
Authors | |
Primary citation | Chen, G.,Xie, H.,You, M.,Liu, J.,Shao, Q.,Li, M.,Su, H.,Xu, Y. Structure-based design of potent FABP4 inhibitors with high selectivity against FABP3. Eur.J.Med.Chem., 264:115984-115984, 2023 Cited by PubMed: 38043490DOI: 10.1016/j.ejmech.2023.115984 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.82 Å) |
Structure validation
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