8WDX

Crystal structure of human FABP4 complexed with C3

8WDX の概要

• エントリーDOI: 10.2210/pdb8wdx/pdb
• 分子名称: Fatty acid-binding protein, adipocyte, 2-[(3-chloranyl-2-phenyl-phenyl)amino]-6-methyl-benzoic acid, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: lipid binding protein-inhibitor complex, lipid binding protein/inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 17311.14

構造登録者

Xie, H.,Chen, G.F.,Xu, Y.C. (登録日: 2023-09-16, 公開日: 2023-12-27)

• 主引用文献: Chen, G.,Xie, H.,You, M.,Liu, J.,Shao, Q.,Li, M.,Su, H.,Xu, Y.; Structure-based design of potent FABP4 inhibitors with high selectivity against FABP3.; Eur.J.Med.Chem., 264:115984-115984, 2023; PubMed: 38043490; DOI: 10.1016/j.ejmech.2023.115984

実験手法

X-RAY DIFFRACTION (1.65 Å)