8W9J

Crystal structure of human CLEC12A ectodomain complexed with 50C1 Fab

8W9J の概要

• エントリーDOI: 10.2210/pdb8w9j/pdb
• 分子名称: Anti-human CLEC12A antibody 50C1 light chain, Anti-human CLEC12A antibody 50C1 heavy chain, C-type lectin domain family 12 member A (3 entities in total)
• 機能のキーワード: c-type lectin receptor, inhibitory antibody, clec12a, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 143004.07

構造登録者

Mori, S.,Nagae, M.,Yamasaki, S. (登録日: 2023-09-05, 公開日: 2024-03-06, 最終更新日: 2024-05-15)

• 主引用文献: Mori, S.,Nagae, M.,Yamasaki, S.; Crystal structure of the complex of CLEC12A and an antibody that interferes with binding of diverse ligands.; Int.Immunol., 36:279-290, 2024; PubMed: 38386511; DOI: 10.1093/intimm/dxae006

実験手法

X-RAY DIFFRACTION (3.5 Å)