8W9I
Crystal structure of bacterial prolyl-tRNA synthetase in complex with inhibitor PAA-5
Summary for 8W9I
Entry DOI | 10.2210/pdb8w9i/pdb |
Descriptor | Proline--tRNA ligase, (2~{S})-~{N}-[3-(4-azanylquinazolin-7-yl)phenyl]sulfonylpyrrolidine-2-carboxamide, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | inhibitor, ligase |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 2 |
Total formula weight | 129630.04 |
Authors | |
Primary citation | Luo, Z.,Zhou, H. Structure-Guided Fluorine Scanning Accelerates the Discovery of Potent and Selective Inhibitors Against Bacterial Prolyl-tRNA Synthetase To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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