8W8G

Crystal structure of human TRF1 with PinX1

Summary for 8W8G

Entry DOI	10.2210/pdb8w8g/pdb
Related	3BQO
Descriptor	Telomeric repeat-binding factor 1, PIN2/TERF1-interacting telomerase inhibitor 1, HEXANE-1,6-DIOL, ... (4 entities in total)
Functional Keywords	telomere, telomerase activity, tumorigenesis, dna binding protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	8
Total formula weight	107383.62
Authors	Lei, M.,Wu, J. (deposition date: 2023-09-02, release date: 2024-09-04)
Primary citation	Lei, M.,Wu, J. PinX1 suppress tumorigenesis through inhibiting telomerase activity To Be Published,
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation