8VZI

Crystal Structure of 2-Hydroxyacyl-CoA Lyase/Synthase CcHACS from Conidiobolus coronatus in the Complex with THDP and ADP

Summary for 8VZI

Entry DOI	10.2210/pdb8vzi/pdb
Descriptor	2-hydroxyacyl-CoA lyase-like protein 1, FORMIC ACID, THIAMINE DIPHOSPHATE, ... (11 entities in total)
Functional Keywords	2-hydroxyacyl-coa lyase/synthase, acyloin condensation, eberlight, lyase
Biological source	Conidiobolus coronatus NRRL 28638
Total number of polymer chains	4
Total formula weight	251349.84
Authors	Kim, Y.,Gade, P.,Endres, M.,Lee, S.,Yoshikuni, Y.,Gonzalez, R.,Michalska, K.,Joachimiak, A. (deposition date: 2024-02-11, release date: 2024-10-02)
Primary citation	Kim, Y.,Lee, S.H.,Gade, P.,Nattermann, M.,Maltseva, N.,Endres, M.,Chen, J.,Wichmann, P.,Hu, Y.,Marchal, D.G.,Yoshikuni, Y.,Erb, T.J.,Gonzalez, R.,Michalska, K.,Joachimiak, A. Revealing reaction intermediates in one-carbon elongation by thiamine diphosphate/CoA-dependent enzyme family. Commun Chem, 7:160-160, 2024 Cited by PubMed: 39034323 DOI: 10.1038/s42004-024-01242-y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation