8VZI

Crystal Structure of 2-Hydroxyacyl-CoA Lyase/Synthase CcHACS from Conidiobolus coronatus in the Complex with THDP and ADP

8VZI の概要

• エントリーDOI: 10.2210/pdb8vzi/pdb
• 分子名称: 2-hydroxyacyl-CoA lyase-like protein 1, FORMIC ACID, THIAMINE DIPHOSPHATE, ... (11 entities in total)
• 機能のキーワード: 2-hydroxyacyl-coa lyase/synthase, acyloin condensation, eberlight, lyase
• 由来する生物種: Conidiobolus coronatus NRRL 28638
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 251349.84

構造登録者

Kim, Y.,Gade, P.,Endres, M.,Lee, S.,Yoshikuni, Y.,Gonzalez, R.,Michalska, K.,Joachimiak, A. (登録日: 2024-02-11, 公開日: 2024-10-02)

• 主引用文献: Kim, Y.,Lee, S.H.,Gade, P.,Nattermann, M.,Maltseva, N.,Endres, M.,Chen, J.,Wichmann, P.,Hu, Y.,Marchal, D.G.,Yoshikuni, Y.,Erb, T.J.,Gonzalez, R.,Michalska, K.,Joachimiak, A.; Revealing reaction intermediates in one-carbon elongation by thiamine diphosphate/CoA-dependent enzyme family.; Commun Chem, 7:160-160, 2024; PubMed: 39034323; DOI: 10.1038/s42004-024-01242-y

実験手法

X-RAY DIFFRACTION (1.85 Å)