8VYM
Soluble ectodomain of human cytomegalovirus (HCMV) glycoprotein B (gB) in the postfusion conformation in complex with 1G2 and 7H3 Fabs
Summary for 8VYM
Entry DOI | 10.2210/pdb8vym/pdb |
EMDB information | 43667 |
Descriptor | Envelope glycoprotein B, 1G2 Fab Heavy Chain, 1G2 Fab Light Chain, ... (8 entities in total) |
Functional Keywords | orthoherpesvirus, betaherpesvirus, cytomegalovirus, human betaherpesvirus 5, human cytomegalovirus, hcmv, glycoprotein b, gb, hcmv gb, viral protein, 7h3, 1g2, viral protein-immune system complex, viral protein/immune system |
Biological source | Human betaherpesvirus 5 More |
Total number of polymer chains | 11 |
Total formula weight | 465492.55 |
Authors | |
Primary citation | Sponholtz, M.R.,Byrne, P.O.,Lee, A.G.,Ramamohan, A.R.,Goldsmith, J.A.,McCool, R.S.,Zhou, L.,Johnson, N.V.,Hsieh, C.L.,Connors, M.,Karthigeyan, K.P.,Crooks, C.M.,Fuller, A.S.,Campbell, J.D.,Permar, S.R.,Maynard, J.A.,Yu, D.,Bottomley, M.J.,McLellan, J.S. Structure-based design of a soluble human cytomegalovirus glycoprotein B antigen stabilized in a prefusion-like conformation. Proc.Natl.Acad.Sci.USA, 121:e2404250121-e2404250121, 2024 Cited by PubMed: 39231203DOI: 10.1073/pnas.2404250121 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
Download full validation report