8VXN

Human Bcl-2/Bcl-xL Chimera Fused to Maltose-Binding Protein

Summary for 8VXN

• Entry DOI: 10.2210/pdb8vxn/pdb
• Related: 8VWX 8VWZ 8VXM
• Descriptor: Maltose/maltodextrin-binding periplasmic protein fused to apoptosis regulator Bcl-2/Bcl-xL chimera (2 entities in total)
• Functional Keywords: apoptosis, bcl-2, mbp fusion, bcl-xl chimera
• Biological source: Escherichia coli (strain K12); More
• Total number of polymer chains: 1
• Total formula weight: 61260.82

Authors

Baird, J.,Holliday, M. (deposition date: 2024-02-05, release date: 2024-10-02)

• Primary citation: Sun, Y.,Houde, D.,Iacob, R.E.,Baird, J.,Swift, R.V.,Holliday, M.,Shi, X.,Sidoli, S.,Brenowitz, M.; Complementary Backbone and Side-Chain Analysis of Drug-Protein Interactions: Combining Hydrogen/Deuterium Exchange and Protein Oxidative Footprinting to Discriminate the Binding of Small Molecule Therapeutics; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.09 Å)