8VXB

Structure of ANT(6)-Ib from Campylobacter fetus subsp fetus complexed with hydrated streptomycin

Summary for 8VXB

• Entry DOI: 10.2210/pdb8vxb/pdb
• Descriptor: Streptomycin aminoglycoside adenylyltransferase ant(6)-Ib, [(2~{S},3~{S},4~{S},5~{R},6~{S})-2-[(2~{R},3~{R},4~{R},5~{S})-2-[(1~{R},2~{S},3~{R},4~{R},5~{S},6~{R})-2,4-bis[[azaniumylidene(azanyl)methyl]amino]-3,5,6-tris(oxidanyl)cyclohexyl]oxy-4-[bis(oxidanyl)methyl]-5-methyl-4-oxidanyl-oxolan-3-yl]oxy-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-3-yl]-methyl-azanium, PHOSPHATE ION, ... (4 entities in total)
• Functional Keywords: campylobacter, streptomycin, antibiotic resistance, transferase
• Biological source: Campylobacter fetus subsp. fetus
• Total number of polymer chains: 1
• Total formula weight: 37215.36

Authors

Nalam, P.,Cook, P.,Smith, B. (deposition date: 2024-02-04, release date: 2024-09-18)

• Primary citation: Nalam, P.,Cook, P.D.,Smith, B.A.; Structural and Biochemical Characterization of Aminoglycoside Nucleotidyltransferase(6)-Ib From Campylobacter fetus subsp. fetus.; Proteins, 2024; PubMed: 39246239; DOI: 10.1002/prot.26745

Experimental method

X-RAY DIFFRACTION (1.85 Å)