8VX0

CRYSTAL STRUCTURE OF CYP2C9*14 IN COMPLEX WITH LOSARTAN

Summary for 8VX0

• Entry DOI: 10.2210/pdb8vx0/pdb
• Descriptor: Cytochrome P450 2C9, [2-butyl-5-chloranyl-3-[[4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol, POTASSIUM ION, ... (6 entities in total)
• Functional Keywords: cytochrome p450 2c9, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 55398.71

Authors

Shah, M.B. (deposition date: 2024-02-02, release date: 2024-06-12, Last modification date: 2024-06-26)

• Primary citation: Parikh, S.J.,Edara, S.,Deodhar, S.,Singh, A.K.,Maekawa, K.,Zhang, Q.,Glass, K.C.,Shah, M.B.; Structural and biophysical analysis of cytochrome P450 2C9*14 and *27 variants in complex with losartan.; J.Inorg.Biochem., 258:112622-112622, 2024; PubMed: 38852293; DOI: 10.1016/j.jinorgbio.2024.112622

Experimental method

X-RAY DIFFRACTION (3.05 Å)