8VWW

CCHFV GP38 bound to ADI-46152 and ADI-58048 Fabs

8VWW の概要

• エントリーDOI: 10.2210/pdb8vww/pdb
• EMDBエントリー: 43604
• 分子名称: GP38, ADI-46152 Fab Heavy Chain, ADI-46152 Fab Light Chain, ... (5 entities in total)
• 機能のキーワード: cchfv, gp38, antibody, immunology, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Crimean-Congo hemorrhagic fever virus strain IbAr10200; 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 124726.16

構造登録者

Hjorth, C.K.,McLellan, J.S. (登録日: 2024-02-02, 公開日: 2024-07-24)

• 主引用文献: Shin, O.S.,Monticelli, S.R.,Hjorth, C.K.,Hornet, V.,Doyle, M.,Abelson, D.,Kuehne, A.I.,Wang, A.,Bakken, R.R.,Mishra, A.K.,Middlecamp, M.,Champney, E.,Stuart, L.,Maurer, D.P.,Li, J.,Berrigan, J.,Barajas, J.,Balinandi, S.,Lutwama, J.J.,Lobel, L.,Zeitlin, L.,Walker, L.M.,Dye, J.M.,Chandran, K.,Herbert, A.S.,Pauli, N.T.,McLellan, J.S.; Crimean-Congo hemorrhagic fever survivors elicit protective non-neutralizing antibodies that target 11 overlapping regions on glycoprotein GP38.; Cell Rep, 43:114502-114502, 2024; PubMed: 39002130; DOI: 10.1016/j.celrep.2024.114502

実験手法

ELECTRON MICROSCOPY (3.9 Å)