8VWM

A structural study of selectivity mechanisms for JNK3 and p38 alpha with indazole scaffold probing compounds

8VWM の概要

• エントリーDOI: 10.2210/pdb8vwm/pdb
• 分子名称: Mitogen-activated protein kinase 14, (4P)-4-{6-[(azetidin-1-yl)methyl]-5-(2-chloro-6-fluoroanilino)-1H-indazol-1-yl}-N-methylthiophene-2-carboxamide, octyl beta-D-glucopyranoside, ... (4 entities in total)
• 機能のキーワード: c-jun terminal kinase 3, jnk3, p38 alpha, kinase, selectivity, transferase
• 由来する生物種: Mus musculus (house mouse)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43292.82

構造登録者

Park, H.,Feng, Y. (登録日: 2024-02-01, 公開日: 2025-02-05)

• 主引用文献: Park, H.,Feng, Y.; A structural study of selectivity mechanisms for JNK3 and p38 alpha with indazole scaffold probing compounds; To Be Published,

実験手法

X-RAY DIFFRACTION (1.94 Å)