8VT3

cryo-EM structure of HMPV (MPV-2cREKR)

Summary for 8VT3

Entry DOI	10.2210/pdb8vt3/pdb
EMDB information	43517
Descriptor	Prefusion of HMPV (MPV-2cREKR), N-fragment, Prefusion of HMPV (MPV-2cREKR), C-fragment, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	prefusion, hmpv, cryo-em, virus, viral protein
Biological source	Human metapneumovirus More
Total number of polymer chains	6
Total formula weight	154182.65
Authors	Yu, X.,Langedijk, J.P.M. (deposition date: 2024-01-25, release date: 2024-07-31, Last modification date: 2024-08-07)
Primary citation	Bakkers, M.J.G.,Ritschel, T.,Tiemessen, M.,Dijkman, J.,Zuffiano, A.A.,Yu, X.,van Overveld, D.,Le, L.,Voorzaat, R.,van Haaren, M.M.,de Man, M.,Tamara, S.,van der Fits, L.,Zahn, R.,Juraszek, J.,Langedijk, J.P.M. Efficacious human metapneumovirus vaccine based on AI-guided engineering of a closed prefusion trimer. Nat Commun, 15:6270-6270, 2024 Cited by PubMed: 39054318 DOI: 10.1038/s41467-024-50659-5 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.33 Å)

Structure validation