8VT3

cryo-EM structure of HMPV (MPV-2cREKR)

Summary for 8VT3

• Entry DOI: 10.2210/pdb8vt3/pdb
• EMDB information: 43517
• Descriptor: Prefusion of HMPV (MPV-2cREKR), N-fragment, Prefusion of HMPV (MPV-2cREKR), C-fragment, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: prefusion, hmpv, cryo-em, virus, viral protein
• Biological source: Human metapneumovirus; More
• Total number of polymer chains: 6
• Total formula weight: 154182.65

Authors

Yu, X.,Langedijk, J.P.M. (deposition date: 2024-01-25, release date: 2024-07-31)

• Primary citation: Bakkers, M.J.G.,Ritschel, T.,Tiemessen, M.,Dijkman, J.,Zuffiano, A.A.,Yu, X.,Overveld, D.,Le, L.,Voorzaat, R.,Haaren, M.,Man, M.,Sharma, S.,Tamara, S.,Fits, L.,Zahn, R.,Juraszek, J.,Langedijk, J.P.M.; Efficacious human metapneumovirus vaccine based on AI-guided engineering of a closed prefusion trimer; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.33 Å)