8VS7

Crystal structure of ADI-19425 Fab in complex with anti-idiotypic 2C1 Fab

Summary for 8VS7

• Entry DOI: 10.2210/pdb8vs7/pdb
• Descriptor: 2C1 Light Chain, 2C1 Heavy Chain, ADI-19425 Heavy Chain, ... (7 entities in total)
• Functional Keywords: rsv, antibody, anti-idiotype, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 96578.27

Authors

Kher, G.,Homad, L.J.,McGuire, A.T.,Pancera, M. (deposition date: 2024-01-23, release date: 2024-09-18, Last modification date: 2024-11-06)

• Primary citation: Scharffenberger, S.,McGuire, A.T.; A novel RSV vaccine candidate derived from anti-idiotypic antibodies targets putative neutralizing B-cells in bulk PBMCs; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.41 Å)