8VRI
E. coli peptidyl-prolyl cis-trans isomerase containing difluoro-leucines
Summary for 8VRI
Entry DOI | 10.2210/pdb8vri/pdb |
Descriptor | Peptidyl-prolyl cis-trans isomerase B, DI(HYDROXYETHYL)ETHER, TRIETHYLENE GLYCOL, ... (8 entities in total) |
Functional Keywords | peptidyl-prolyl cis-trans isomerase, non-canonical amino acids, fluorinated leucine, isomerase |
Biological source | Escherichia coli More |
Total number of polymer chains | 5 |
Total formula weight | 98040.58 |
Authors | Frkic, R.L.,Jackson, C.J. (deposition date: 2024-01-22, release date: 2024-05-22, Last modification date: 2024-06-19) |
Primary citation | Frkic, R.L.,Tan, Y.J.,Abdelkader, E.H.,Maleckis, A.,Tarcoveanu, E.,Nitsche, C.,Otting, G.,Jackson, C.J. Conformational Preferences of the Non-Canonical Amino Acids (2 S ,4 S )-5-Fluoroleucine, (2 S ,4 R )-5-Fluoroleucine, and 5,5'-Difluoroleucine in a Protein. Biochemistry, 63:1388-1394, 2024 Cited by PubMed: 38742763DOI: 10.1021/acs.biochem.4c00081 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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