8VQC
Structure of the voltage-gated sodium channel NavPas from American Cockroach Periplaneta Americana in complex with scorpion alpha-toxin LqhaIT
Summary for 8VQC
Entry DOI | 10.2210/pdb8vqc/pdb |
EMDB information | 43438 |
Descriptor | Sodium channel protein PaFPC1, Alpha-insect toxin LqhaIT, beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | navpas, scorpion toxin, ion channel, voltage-gated sodium channel, membrane protein |
Biological source | Periplaneta americana (American cockroach) More |
Total number of polymer chains | 2 |
Total formula weight | 194647.00 |
Authors | Phulera, S.,Khoshouei, M.,Whicher, J.,Weihofen, W.A. (deposition date: 2024-01-18, release date: 2024-09-04) |
Primary citation | Phulera, S.,Dickson, C.J.,Schwalen, C.J.,Khoshouei, M.,Cassell, S.J.,Sun, Y.,Condos, T.,Whicher, J.,Weihofen, W.A. Scorpion alpha-toxin Lqh alpha IT specifically interacts with a glycan at the pore domain of voltage-gated sodium channels. Structure, 2024 Cited by PubMed: 39181123DOI: 10.1016/j.str.2024.07.021 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.9 Å) |
Structure validation
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