8VQ9

Prefusion stabilized structure of the SARS-CoV-2 fusion machinery

8VQ9 の概要

• エントリーDOI: 10.2210/pdb8vq9/pdb
• EMDBエントリー: 43435
• 分子名称: Spike protein S2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: sarbecoviruses, spike glycoprotein, fusion protein, prefusion-stabilized, seattle structural genomics center for infectious disease, ssgcid, viral protein
• 由来する生物種: Sarbecovirus
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 210483.04

構造登録者

Lee, J.,Veesler, D.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2024-01-18, 公開日: 2024-07-24)

• 主引用文献: Lee, J.,Stewart, C.,Schafer, A.,Leaf, E.M.,Park, Y.J.,Asarnow, D.,Powers, J.M.,Treichel, C.,Sprouse, K.R.,Corti, D.,Baric, R.,King, N.P.,Veesler, D.; A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines.; Nat Commun, 15:5496-5496, 2024; PubMed: 38944664; DOI: 10.1038/s41467-024-49656-5

実験手法

ELECTRON MICROSCOPY (2.7 Å)