8VQ6

hCA-II-4-(2-Aminoethyl)benzenesulfonamide-complex. Two molecules of inhibitor bound to active site and secondary binding pocket

8VQ6 の概要

• エントリーDOI: 10.2210/pdb8vq6/pdb
• 関連するPDBエントリー: 8VQ5 8VQ7
• 分子名称: Carbonic anhydrase 2, ZINC ION, 4-(2-AMINOETHYL)BENZENESULFONAMIDE, ... (4 entities in total)
• 機能のキーワード: carbonic anhydrase ii, human carbonic anhydrase ii, carbon anhydrase, two pockets bound, binding pocket, binding pockets, active site, small molecule, bivalent, complex, protein ligand complex, protein inhibition, inhibitor, binder, nano molar binder, nano molar inhibitor, protein binding, 4-(2-aminoethyl)benzenesulfonamide, secondary binding site, zyx, lyase-inhibitor complex, lyase/inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29955.25

構造登録者

Ismail, M.M. (登録日: 2024-01-17, 公開日: 2025-07-16)

• 主引用文献: Ismail, M.M.; SBDD of Carbonic Anhydrase II Inhibitors; To Be Published,

実験手法

X-RAY DIFFRACTION (1.45 Å)