8VLY

Cryo-EM structure of human HGSNAT in transition state

Summary for 8VLY

• Entry DOI: 10.2210/pdb8vly/pdb
• EMDB information: 43348
• Descriptor: Heparan-alpha-glucosaminide N-acetyltransferase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: membrane protein, lysosome, transmembrane acetyltransferase, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 148260.52

Authors

Li, F.,Zhao, B. (deposition date: 2024-01-12, release date: 2024-06-26)

• Primary citation: Li, F.; Structural and mechanistic insights into a lysosomal membrane enzyme HGSNAT involved in Sanfilippo syndrome; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.61 Å)