8VLY

Cryo-EM structure of human HGSNAT in transition state

8VLY の概要

• エントリーDOI: 10.2210/pdb8vly/pdb
• EMDBエントリー: 43348
• 分子名称: Heparan-alpha-glucosaminide N-acetyltransferase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: membrane protein, lysosome, transmembrane acetyltransferase, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 148260.52

構造登録者

Li, F.,Zhao, B. (登録日: 2024-01-12, 公開日: 2024-06-26)

• 主引用文献: Li, F.; Structural and mechanistic insights into a lysosomal membrane enzyme HGSNAT involved in Sanfilippo syndrome; To Be Published,

実験手法

ELECTRON MICROSCOPY (3.61 Å)