8VLK

Crystal structure of the yeast cytosine deaminase containing both open and closed active sites

Summary for 8VLK

• Entry DOI: 10.2210/pdb8vlk/pdb
• Descriptor: Cytosine deaminase, 1,2-ETHANEDIOL, ZINC ION, ... (5 entities in total)
• Functional Keywords: cytosine deaminase, resistance, heterodimer, antifungal protein
• Biological source: Saccharomyces cerevisiae (brewer's yeast)
• Total number of polymer chains: 4
• Total formula weight: 72075.36

Authors

Picard, M.-E.,Grenier, J.,Despres, P.C.,Dube, A.K.,Landry, C.R.,Shi, R. (deposition date: 2024-01-11, release date: 2024-08-21)

• Primary citation: Despres, P.C.,Dube, A.K.,Picard, M.-E.,Grenier, J.,Shi, R.,Landry, C.R.; Compensatory mutations potentiate constructive neutral evolution by gene duplication; Science, 2024; DOI: 10.1126/science.ado5719

Experimental method