8VLJ
Crystal structure of the cacodylate-bound yeast cytosine deaminase (closed form)
Summary for 8VLJ
Entry DOI | 10.2210/pdb8vlj/pdb |
Descriptor | Cytosine deaminase, CACODYLATE ION, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | cytosine deaminase, resistance, heterodimer, antifungal protein |
Biological source | Saccharomyces cerevisiae (brewer's yeast) |
Total number of polymer chains | 2 |
Total formula weight | 36176.52 |
Authors | Picard, M.-E.,Grenier, J.,Despres, P.C.,Dube, A.K.,Landry, C.R.,Shi, R. (deposition date: 2024-01-11, release date: 2024-08-21, Last modification date: 2024-09-04) |
Primary citation | Despres, P.C.,Dube, A.K.,Picard, M.E.,Grenier, J.,Shi, R.,Landry, C.R. Compensatory mutations potentiate constructive neutral evolution by gene duplication. Science, 385:770-775, 2024 Cited by PubMed: 39146405DOI: 10.1126/science.ado5719 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.39 Å) |
Structure validation
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