8VK1

X-ray crystal structure of human IgE 4C8 Fab complex with Der p 2.0103

Summary for 8VK1

Entry DOI	10.2210/pdb8vk1/pdb
Descriptor	IgE 4C8 light chain, Der p 2 variant 3, IgE 4C8 heavy chain, ... (4 entities in total)
Functional Keywords	dust mite allergy, house dust mite, der p 2-ige complex, human ige against der p 2, antibody-allergen complex, antibody-allergen interaction, allergen-immune system complex, allergen/immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	122156.94
Authors	Khatri, K.,Ball, A.,Smith, S.A.,Champan, M.D.,Pomes, A.,Chruszcz, M. (deposition date: 2024-01-08, release date: 2024-06-19)
Primary citation	Ball, A.,Khatri, K.,Glesner, J.,Vailes, L.D.,Wunschmann, S.,Gabel, S.A.,Mueller, G.A.,Zhang, J.,Peebles Jr., R.S.,Chapman, M.D.,Smith, S.A.,Chruszcz, M.,Pomes, A. Structural analysis of human IgE monoclonal antibody epitopes on dust mite allergen Der p 2. J.Allergy Clin.Immunol., 2024 Cited by PubMed: 38697404 DOI: 10.1016/j.jaci.2024.04.017 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.05 Å)

Structure validation