8VHH
Engineered holo tryptophan synthase (Tm9D8*) derived from T. maritima TrpB
Summary for 8VHH
Entry DOI | 10.2210/pdb8vhh/pdb |
Descriptor | Tryptophan synthase beta chain 1, PYRIDOXAL-5'-PHOSPHATE, POTASSIUM ION, ... (5 entities in total) |
Functional Keywords | enzyme, synthase, tryptophan synthases, engineered enzyme, lyase |
Biological source | Thermotoga maritima |
Total number of polymer chains | 2 |
Total formula weight | 88767.71 |
Authors | Porter, N.J.,Johnston, K.E.,Almhjell, P.J.,Arnold, F.H. (deposition date: 2024-01-02, release date: 2024-08-14) |
Primary citation | Johnston, K.E.,Almhjell, P.J.,Watkins-Dulaney, E.J.,Liu, G.,Porter, N.J.,Yang, J.,Arnold, F.H. A combinatorially complete epistatic fitness landscape in an enzyme active site. Proc.Natl.Acad.Sci.USA, 121:e2400439121-e2400439121, 2024 Cited by PubMed: 39074291DOI: 10.1073/pnas.2400439121 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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