8VG5
Crystal Structure of V113N Variant of D-Dopachrome Tautomerase (D-DT) Bound with 4CPPC
Summary for 8VG5
Entry DOI | 10.2210/pdb8vg5/pdb |
Descriptor | D-dopachrome decarboxylase, 4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid, CITRIC ACID, ... (4 entities in total) |
Functional Keywords | truncation, enzyme, cytokine, isomerase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 50913.34 |
Authors | Parkins, A.,Pilien, A.,Thompson, M.C.,Pantouris, G. (deposition date: 2023-12-22, release date: 2024-05-01, Last modification date: 2024-05-22) |
Primary citation | Parkins, A.,Pilien, A.V.R.,Wolff, A.M.,Argueta, C.,Vargas, J.,Sadeghi, S.,Franz, A.H.,Thompson, M.C.,Pantouris, G. The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes. J.Med.Chem., 67:7359-7372, 2024 Cited by PubMed: 38670943DOI: 10.1021/acs.jmedchem.4c00177 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
Download full validation report