8VFZ
Cryo-EM structure of FoxA1 in complex with ALBN1 nucleosome (class 2)
Summary for 8VFZ
Entry DOI | 10.2210/pdb8vfz/pdb |
EMDB information | 43195 |
Descriptor | Hepatocyte nuclear factor 3-alpha, DNA (171-MER), Histone H2A type 1-B/E, ... (7 entities in total) |
Functional Keywords | nucleosome, pioneer transcription factors, dna binding proteins, transcription, chromatin, nuclear protein, nuclear protein-dna complex, nuclear protein/dna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 12 |
Total formula weight | 324737.30 |
Authors | Zhou, B.R.,Bai, Y. (deposition date: 2023-12-22, release date: 2024-08-07, Last modification date: 2024-09-11) |
Primary citation | Zhou, B.R.,Feng, H.,Huang, F.,Zhu, I.,Portillo-Ledesma, S.,Shi, D.,Zaret, K.S.,Schlick, T.,Landsman, D.,Wang, Q.,Bai, Y. Structural insights into the cooperative nucleosome recognition and chromatin opening by FOXA1 and GATA4. Mol.Cell, 84:3061-, 2024 Cited by PubMed: 39121853DOI: 10.1016/j.molcel.2024.07.016 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.1 Å) |
Structure validation
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