8VFC
Binary DNA Polymerase Beta bound to DNA containing primer terminal T base-paired with FapydG
Summary for 8VFC
Entry DOI | 10.2210/pdb8vfc/pdb |
Descriptor | DNA polymerase beta, DNA (5'-D(*CP*CP*GP*AP*CP*GP*(FAP)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-3'), ... (6 entities in total) |
Functional Keywords | fapydg, polymerase beta, primer terminus, pol beta, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 47746.85 |
Authors | Oden, P.N.,Ryan, B.J.,Freudenthal, B.D. (deposition date: 2023-12-21, release date: 2024-05-08, Last modification date: 2024-06-05) |
Primary citation | Gao, S.,Oden, P.N.,Ryan, B.J.,Yang, H.,Freudenthal, B.D.,Greenberg, M.M. Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta. Nucleic Acids Res., 52:5392-5405, 2024 Cited by PubMed: 38634780DOI: 10.1093/nar/gkae277 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.48 Å) |
Structure validation
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