8VEJ
De novo designed cholic acid binder: CHD_buttress
Summary for 8VEJ
Entry DOI | 10.2210/pdb8vej/pdb |
Descriptor | CHD_buttress, CHOLIC ACID (2 entities in total) |
Functional Keywords | de novo designed protein, cholic acid, small molecule binder, de novo protein |
Biological source | synthetic construct |
Total number of polymer chains | 2 |
Total formula weight | 55766.08 |
Authors | Bera, A.K.,Tran, L.,Kang, A.,Baker, D. (deposition date: 2023-12-19, release date: 2024-07-17, Last modification date: 2024-07-31) |
Primary citation | An, L.,Said, M.,Tran, L.,Majumder, S.,Goreshnik, I.,Lee, G.R.,Juergens, D.,Dauparas, J.,Anishchenko, I.,Coventry, B.,Bera, A.K.,Kang, A.,Levine, P.M.,Alvarez, V.,Pillai, A.,Norn, C.,Feldman, D.,Zorine, D.,Hicks, D.R.,Li, X.,Sanchez, M.G.,Vafeados, D.K.,Salveson, P.J.,Vorobieva, A.A.,Baker, D. Binding and sensing diverse small molecules using shape-complementary pseudocycles. Science, 385:276-282, 2024 Cited by PubMed: 39024436DOI: 10.1126/science.adn3780 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.59 Å) |
Structure validation
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