8VCV

Lineage IV Lassa virus glycoprotein (Josiah) in complex with rabbit polyclonal antibody (GPC-C epitope)

Summary for 8VCV

• Entry DOI: 10.2210/pdb8vcv/pdb
• EMDB information: 43141
• Descriptor: Glycoprotein G1, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total)
• Functional Keywords: lassa, polyclonal antibody, gpc-c, glycoprotein, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Lassa virus Josiah; More
• Total number of polymer chains: 8
• Total formula weight: 256539.05

Authors

Brouwer, P.J.M.,Perrett, H.R.,Ward, A.B. (deposition date: 2023-12-14, release date: 2024-09-25)

• Primary citation: Brouwer, P.J.M.,Perrett, H.R.,Beaumont, T.,Nijhuis, H.,Kruijer, S.,Burger, J.A.,Bontjer, I.,Lee, W.H.,Ferguson, J.A.,Schauflinger, M.,Muller-Krauter, H.,Sanders, R.W.,Strecker, T.,van Gils, M.J.,Ward, A.B.; Defining bottlenecks and opportunities for Lassa virus neutralization by structural profiling of vaccine-induced polyclonal antibody responses.; Cell Rep, 43:114708-114708, 2024; PubMed: 39243373; DOI: 10.1016/j.celrep.2024.114708

Experimental method

ELECTRON MICROSCOPY (2.8 Å)