8VAW

Magnesium catalyzed primer extension product with 14mer primer and mixed phosphorothioate activated G monomer

Summary for 8VAW

Entry DOI	10.2210/pdb8vaw/pdb
Descriptor	Magnesium catalyzed nonenzymatic RNA primer extension product, MAGNESIUM ION, 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, ... (4 entities in total)
Functional Keywords	phosphorothioate, magnesium, oxophilic metal ion, nonenzymatic primer extension, rna
Biological source	synthetic construct
Total number of polymer chains	2
Total formula weight	10539.81
Authors	Fang, Z.,Szostak, J.W. (deposition date: 2023-12-11, release date: 2024-04-17, Last modification date: 2024-05-01)
Primary citation	Fang, Z.,Pazienza, L.T.,Zhang, J.,Tam, C.P.,Szostak, J.W. Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension. J.Am.Chem.Soc., 146:10632-10639, 2024 Cited by PubMed: 38579124 DOI: 10.1021/jacs.4c00323 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.25 Å)

Structure validation